陈飞副研究员
陈飞 (Fei Chen)
Associate Professor
Institute of Chemistry, Chinese Academy of Sciences (CAS), P. R. China
Zhongguancun North First Street 2,100190 Beijing, P. R. China
Tel: 86-010-82362742 (office)
E-mail: chenfei211@iccas.ac.cn
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Educational Background
2016.3-present, Associate Professor, Institute of Chemistry, Chinese Academy of Sciences (CAS), P. R. China
2012.7-2016.3, Assistant Professor, Institute of Chemistry, Chinese Academy of Sciences (CAS), P. R. China
2007.9-2012.7, Ph. D. in organic chemistry, Institute of Chemistry, Chinese Academy of Sciences (CAS), P. R. China, advisor Prof. Qing-Hua Fan
2002.9-2006.7, B.S. in chemistry, Northeast Normal University, P. R. China, advisor Prof. Qun Liu
Research Interests
Asymmetric catalysis
Synthesis of biologically active heterocyclic compounds
Awards
Youth Innovation Promotion Association, CAS, 2017
The First Prize Scholarship of Director, Institute of Chemistry, Chinese Academy of Sciences (CAS), 2011
The Second Prize Scholarship of Hang Zhou Tai Da, 2011
Merit Student of Chinese Academy of Sciences, 2010
Representative Publications
17. Zhusheng Yang, Fei Chen,* Yanmei He, Nianfa Yang and Qing-Hua Fan,* "Highly Enantioselective Synthesis of Indolines: Asymmetric Hydrogenation at Ambient Temperature and Pressure with Cationic Ruthenium Diamine Catalysts", Angew. Chem. Int. Ed. 2016, 55,13863–13866.
16. Wenpeng Ma, Jianwei Zhang, Cong Xu, Fei Chen, Yan-Mei He and Qing-Hua Fan,* "Highly Enantioselective Direct Synthesis of Endocyclic Vicinal Diamines through Chiral Ru(diamine)-Catalyzed Hydrogenation of 2,2'-Bisquinoline Derivatives" Angew. Chem. Int. Ed. 2016, 55, 12891-12894.
15. Wenpeng Ma, Fei Chen, Youran Liu, Yan-Mei He, and Qing-Hua Fan,* "Ruthenium-Catalyzed Enantioselective Hydrogenation of 1,8-Naphthyridine Derivatives" Org. Lett. 2016, 18, 2730–2733.
14. Jianwei Zhang, Fei Chen, Yan-Mei He, Qing-Hua Fan,* "Asymmetric Ruthenium-Catalyzed Hydrogenation of 2,6-Disubstituted 1,5-Naphthyridines: Access to Chiral 1,5-Diaza-cis-Decalins", Angew. Chem. Int. Ed. 2015, 54, 4622-4625.
13. Fei Chen, Zi-Yuan Ding, Yan-Mei He, Qing-Hua Fan,* "Synthesis of Optically Active 1,2,3,4-Tetrahydroquinolines viaAsymmetric Hydrogenation Using Iridium-Diamine Catalyst", Org. Synth. 2015, 92, 213-226.
12. Zhusheng Yang, Fei Chen,* Yan-Mei He, Nianfa Yang*, Qing-Hua Fan,* "Efficient asymmetric hydrogenation of quinolines in neat water catalyzed by chiral cationic Ru-diamine complexes", Catal. Sci. Technol. 2014, 4, 2887-2890.
11. Jie Qin, Fei Chen, Yan-Mei He, Qing-Hua Fan,* "Asymmetric hydrogenation of 3-substituted 2H-1,4-benzoxazines with chiral cationic Ru-MsDPEN catalysts: remarkable counteranion effect", Org. Chem. Front. 2014, 1, 952-955.
10. Yong Li, Yanmei He, Fei Chen, Qinghua Fan*, "Asymmetric Hydrogenation of 2-Aryl-5,6-dihydropyrazine Derivatives with Chiral Cationic Ruthenium Diamine Catalysts", Chin. J. Chem. 2014, 32, 991-994.
9. Zi-Yuan Ding, Tianli Wang, Yan-Mei He, Fei Chen, Hai-Feng Zhou, Qing-Hua Fan,* Qingxiang Guo,* and Albert S. C. Chan, "Highly Enantioselective Synthesis of Chiral Tetrahydroquinolines and Tetrahydroisoquinolines by Ruthenium-Catalyzed Asymmetric Hydrogenation in Ionic Liquid", Adv. Synth. Catal. 2013, 355, 3727-3735.
8. Tianli Wang, Fei Chen, Jie Qin, Yan-Mei He and Qing-Hua Fan,* "Asymmetric Ruthenium-Catalyzed Hydrogenation of 2- and 2,9-Substituted 1,10-Phenanthrolines", Angew. Chem. Int. Ed. 2013, 52, 7172-7176.
7. Fei Chen, Ziyuan Ding, Yanmei He, Jie Qin, Tianli Wang and Qing-Hua Fan,* "Asymmetric Hydrogenation of N-Alkyl and N-Aryl Ketimines using Chiral CationicRu(Diamine) Complexes as Catalysts: The Counteranion and Solvent Effects, and Substrate Scope", Tetrahedron 2012, 68, 5248-5257.
6. Zi-Yuan Ding, Fei Chen, Jie Qin, Yan-Mei He and Qing-Hua Fan,* "Asymmetric Hydrogenation of 2,4-Disubstituted 1,5-Benzodiazepines Using Cationic Ruthenium Diamine Catalysts: An Unusual Achiral Counteranion Induced Reversal of Enantioselectivity", Angew. Chem. Int. Ed. 2012, 51, 5706-5710.
5. Jie Qin, Fei Chen, Ziyuan Ding, Yan-Mei He, Lijin Xu and Qing-Hua Fan,* "Asymmetric Hydrogenation of 2- and 2,3-Substituted Quinoxalines with Chiral Cationic Ruthenium Diamine Catalysts", Org. Lett. 2011, 13, 6568-6571. <Highlight by Synfacts 2012, 8, 191.>
4. Fei Chen, Ziyuan Ding, Jie Qin, Tianli Wang, Yanmei He and Qing-Hua Fan,* "Highly Effective Asymmetric Hydrogenation of Cyclic N-Alkyl Imines with Chiral Cationic Ru-MsDPEN Catalysts", Org. Lett, 2011, 13, 4348-4351. <Highlight by Synfacts 2011, 10, 1092.>
3. Tianli Wang, Lian-Gang Zhuo, Zhiwei Li, Fei Chen, Ziyuan Ding, Yanmei He, Qing-Hua Fan,* Junfeng Xiang, Zhi-Xiang Yu* and Albert S. C. Chan, "Highly Enantioselective Hydrogenation of Quinolines Using Phosphine-Free Chiral Cationic Ruthenium Catalysts: Scope, Mechanism, and Origin of Enantioselectivity", J. Am. Chem. Soc. 2011, 133, 9878-9891.
2. Fei Chen, Tianli Wang, Yanmei He, Ziyuan Ding, Zhiwei Li, Lijin Xu and Qing-Hua Fan,* "Asymmetric Hydrogenation of N-Alkyl Ketimines with Phosphine-Free, Chiral, Cationic Ru-MsDPEN Catalysts", Chem. Eur. J. 2011, 17, 1109-1113. <Highlight by Synfacts 2011, 4, 420.>
1. Fei Chen, Zhiwei Li, Yanmei He and Qing-Hua Fan,* "Asymmetric Hydrogenation of Cyclic N-Sulfonylimines with Phosphine-Free Chiral Cationic Ru-MsDPEN Catalysts", Chin. J. Chem. 2010, 28, 1529-1532.
